The CDC breaks down regions into political departments, and so the department of Loreto, described by the CDC as Iquitos region (Iquitos is the capitol) is regarded as a hotspot for malaria, with over 70,000 cases last year. Facts not mentioned by the CDC: all of these cases come from the Nauta area and zone SSW of Iquitos where brown water forest ecology in which lives Anopheles darlingi mosquito, the only carrier of malarial parasites in Peru. The most recent study (2014) of malaria transmission has identified the artificial fish ponds used for pisciculture in this region as being the major breeding ground for Anopheles darlingi and vector for malarial transmission. We do not have this ecosystem or this particular economic activity close to downtown Iquitos or in the Tahuayo River basin. We do not have any Anopheles darlingi in downtown Iquitos or the Tahuayo River basin. This is because this species does not breed in water with a high concentration of phenolic chemical compounds (so called blackwater or highly acidic water) which dominates the Tahuayo River basin ecosystems. Other facts not mentioned by the CDC: the most effective treatment against one of the four subspecies of Plasmodium falciparum present in Loreto-Nauta zone, is actually resistant to Chloroquine and Malarone and so Larium (98% effective) is now recently recommended for people who work or visit that zone. But Larium also blocks protein synthesis in a way that severely compromises functioning of your immunological, neurological, circulatory, respiratory and digestive systems. Some 20% of Larium users experience severe side effects.